Research Article
Published: 29 August, 2017 | Volume 1 - Issue 1 | Pages: 032-046
Background: The reaction of 2-(benzo]d[thiazol-2-yl)-3-oxopentanedinitrile 4 with DMF/DMA has been investigated to explore the synthetic potentialities of this novel activated nitrile in heterocyclic synthesis.
Results: Pyrano, pyridino, pyrazolo, azepino and oxothiepano carbonitrile derivatives could be obtained starting from 4 and plausible mechanisms for their formations are reported.
Conclusion: The newly synthesized compounds were assessed for their antimicrobial activity. Compounds 7, 10 and 12 exhibited broad spectrum antibacterial profile against the tested organisms.
Read Full Article HTML DOI: 10.29328/journal.aac.1001004 Cite this Article Read Full Article PDF
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